Super Cialis (Dapoxetine & Tadalafil) vs. Other ED & PE Medications: In‑Depth Comparison

Quick Take

• Super Cialis blends dapoxetine (for premature ejaculation) with tadalafil (for erectile dysfunction) in one pill.
• It starts working within 30‑60 minutes and can last up to 36 hours.
• Typical side‑effects include headache, flushing, and mild nausea; serious reactions are rare.
• Alternatives split the treatment - separate PE drug (e.g., Priligy) and ED drug (e.g., Viagra, Cialis).
• Cost and insurance coverage vary widely; online pharmacies may offer lower prices but require a valid prescription.

If you’re weighing Super Cialis against other options, you’re probably curious about two things: how well it tackles both erectile dysfunction (ED) and premature ejaculation (PE) at once, and whether that convenience outweighs potential trade‑offs in side‑effects or cost.

Super Cialis is a combination tablet that pairs dapoxetine, a short‑acting selective serotonin reuptake inhibitor (SSRI) approved for PE, with tadalafil, a phosphodiesterase‑5 (PDE5) inhibitor used for ED. The idea is simple: one pill, two problems solved.

How Dapoxetine Tackles Premature Ejaculation

Dapoxetine works by increasing serotonin levels in the brain, which slows down the ejaculatory reflex. Unlike traditional SSRIs that need weeks to build up, dapoxetine’s short half‑life (about 1.5hours) means it can be taken on demand, 1-3hours before sexual activity. Clinical trials show a 30‑40% increase in intravaginal ejaculation latency time (IELT) compared with placebo.

How Tadalafil Supports Erectile Function

Tadalafil blocks the PDE5 enzyme, allowing cyclic‑GMP to accumulate and keep smooth muscle in the penis relaxed. This promotes blood flow, leading to an erection when sexual stimulation occurs. Its long half‑life (≈17hours) provides a window of up to 36hours, giving users flexibility beyond the classic 4‑hour window of sildenafil (Viagra).

Why Combine Them? The Convenience Factor

For men who experience both ED and PE, managing two separate prescriptions can be a hassle-different dosing schedules, separate pharmacy orders, and multiple insurance claims. A single tablet eliminates the need to remember timing for two drugs and reduces the chance of missing a dose.

Key Alternatives for Erectile Dysfunction

Below is a snapshot of the most common single‑ingredient ED meds that people often stack with a PE treatment like dapoxetine or Priligy.

Key Alternatives for Premature Ejaculation

When it comes to PE, dapoxetine isn’t the only game‑in‑town. The most widely prescribed brand‑name version is Priligy. It shares the same active ingredient and dosing guidelines.

Other strategies include topical anesthetic sprays (e.g., lidocaine‑prilocaine), behavioral techniques (stop‑start, squeeze), and longer‑acting SSRIs taken daily (e.g., sertraline). These alternatives can be combined with any PDE5 inhibitor, but they involve extra steps or longer time to see effect.

Pros and Cons of Super Cialis

Pros

• Convenience: One pill handles both conditions.
• Rapid onset: Dapoxetine works within an hour, tadalafil within the same window.
• Extended window: Up to 36hours of erectile support without re‑dosing.
• Reduced pill burden: Fewer pharmacy trips.

Cons

• Fixed dosage: You can’t adjust dapoxetine and tadalafil amounts independently.
• Side‑effect overlap: Headache, flushing, and nausea may be amplified when both agents act together.
• Cost: Combination tablets are often priced higher than buying generic versions separately.
• Contra‑indications: Nitrates and certain heart conditions rule out tadalafil; dapoxetine isn’t recommended with other serotonergic drugs.

Who Should Consider Super Cialis?

The ideal candidate is a man diagnosed with both ED and PE who prefers a once‑daily or as‑needed regimen that simplifies logistics. Age isn’t a strict barrier, but patients over 65 should have a thorough cardiovascular assessment because tadalafil can affect blood pressure.

A quick checklist before prescribing:

• No use of nitrates (e.g., nitroglycerin) or alpha‑blockers without doctor supervision.
• No severe liver or kidney impairment that could alter drug metabolism.
• Not currently on monoamine oxidase inhibitors (MAOIs) or other SSRIs that might interact with dapoxetine.
• Ability to tolerate potential side‑effects like mild headache or back pain.

Obtaining Super Cialis Safely

Because it’s a prescription‑only medication in the UK, you’ll need a valid prescription from a GP or specialist. Many reputable online pharmacies now offer tele‑consultations, but be wary of sites that sell the product without a doctor’s review. Look for the MHRA registration number and a clear privacy policy.

Pricing varies: a 30‑day supply (eight 20mg tablets) can range from £90 to £150, depending on the pharmacy and whether you have private insurance coverage. Always compare total cost, including delivery fees, before committing.

When to Opt for Separate Medications Instead

If you only have mild PE but robust erectile function, dapoxetine alone (or a topical spray) may be enough, saving you the extra tadalafil exposure. Conversely, men who achieve satisfactory erection quality with occasional use of a PDE5 inhibitor may not need the added PE component.

Separating the drugs also allows dose fine‑tuning. For example, if you find 10mg tadalafil effective but experience dapoxetine‑related nausea, you could lower the dapoxetine dose or switch to a different PE strategy while keeping the same ED dose.

Bottom line: Super Cialis offers a streamlined solution for men battling both ED and PE, but the trade‑off is a fixed dose combo that may not suit everyone. Assess your symptoms, talk to a healthcare professional, and weigh the convenience against possible side‑effects and cost before deciding.